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Case Studies

Case RO 2007 Unilateral

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Case report abstract

We present a case of a 48-year-old female with recurrent floaters and
decreased vision in her right eye. The onset of symptoms was in 2007 when a diagnose
of retinal vasculitis was made. She had no accompanying systemic signs and symptoms
and no history of ocular trauma or previous tuberculosis infection. The eye condition was
managed only with intermittent focal laser treatment, because the general treatment
with steroids was not efficient and poorly tolerated. After the laser treatment, the visual
acuity completely recovered and there was no recurrence of vitreous hemorrhage.
The case particularity was the unilaterality after 9 years from the onset.

Case report content

Original source: Romanian Journal of Ophtalmology – Volume 61 Issue 2 / 2017

Link to case study: https://rjo.ro/wp-content/uploads/2016/07/images_rjo_issue_2_2017_13.nicolcescu_andreea_final_PR.pdf

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Case Studies

Case-USA-1993-Marilyn

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Hi,
I was diagnosed with peripheral proliferative retinopathy when I was 39.

I don’t have diabetes or high blood pressure and I was tested from head to toe. My only test that came back high was a sedimentation rate test.

I had 7 laser surgeries in my left eye and 5 in my right eye. I had hemorrhaging in both eyes. After all of my testing I was told that I had Eales disease.

I have been to four doctors. One at Northwestern University-Dr. Lee Jampol and he recommended Dr. David Orth. I went to Dr. Orth for 20 yrs and now I go to an associate, Dr. Kirk Packo.

I have a partially detached retina from scar tissue pulling on the retina and they are watching it. Dr. Orth no longer operates and that is why I go to Dr. Packo.

I want to go as long as I can without the surgery.
Marilyn Quinn

Resources

Eales disease – current concepts in diagnosis and management

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Eales disease – current concepts in diagnosis
and management

Eye fundus photograph of Eales disease with active periphlebitis
Eye fundus photograph of Eales disease with active periphlebitis

A recent article on Eales Disease, received courtesy of Prof. Dr. Jyotirmay Biswas, Director of Uveitis and Ocular Pathology departments – Sankara Nethralaya

PDF article: Eales’ disease -JOII

Abstract

Eales’ disease, first described by the British ophthalmologist Henry Eales in 1880, is characterized by three overlapping stages of venous inflammation (vasculitis), occlusion, and retinal neovascularization. Diagnosis is mostly clinical and requires exclusion of other systemic or ocular conditions that could present with similar retinal features. In recent years, immunological, molecular biological, and biochemical studies have indicated the role of human leukocyte antigen, retinal autoimmunity, Mycobacterium tuberculosis genome, and free radical-mediated damage in the etiopathogenesis of this disease. However, its etiology appears to be multifactorial. The management depends on the stage of the disease and consists of medical treatment with oral corticosteroids in the active inflammatory stage and laser photocoagulation in the advanced retinal ischemia and neovascularization stages.

External link: http://www.joii-journal.com/content/3/1/11

Case Studies

Case-NL-1983-ED-FH

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Hallo,
In 1983, 31 years old, I was diagnosed Eales disease after some floaters appeared in my left eye. I had several (xenon)laser photocoagulation first in my left eye and later also in my right eye. in the folowing years I had more laser photocoagulation and also cryocoagulation. In both eyes I had a vitrectomiy and in both eyes a lens exchange, in my left eye twice (claw lens).
With regards,
Frits

Case Studies

Case-NL-1998

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I want to now if there are people in the Netherland (Holland) who has the same illness.
Mine Mother had the illness also, and for 14 years ago i have lost my left eye and the right is preopperative, the english is to bad to understand evryting good bye Gerda

Resources

Mycobacterial load in the vitreous of patients

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Purpose: To report mycobacterial load in the vitreous of patients labeled as having Eales’ disease.
Methods: Eighty-eight patients were prospectively enrolled into 3 groups: 28 patients with so-called Eales’ disease (group A); 30 positive controls with specific uveitis syndromes (group B), and 30 negative controls (group C). The undiluted vitreous humor samples were collected and subjected to real-time PCR assay for MPB64 gene of Mycobacterium tuberculosis (MTB) and load quantified.

Results: Sixteen (57.14%) vitreous fluid samples in group A; 1 sample in group B, and none of the samples in group C were positive for MTB genome from the vitreous. The copies of MTB genomes in the positive samples in group A were 1.52 × 104 to 1.01 × 106.

Conclusion: MTB genome was demonstrated in more than 50% of vitreous fluid samples with significant bacillary load, indicating that half of patients with so-called Eales’ disease are indeed cases of tubercular vasculitis.

Read More:
Quantitative Polymerase Chain Reaction for Mycobacterium tuberculosis in So-called Eales’ Disease

Case Studies

Case-IN-2001-ED-Doctor

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India/2001/Eales Disease/Dr.C.S.T
Blind doctor set to practice medicine

DNIS News Network – Dr Toppo, who became the first blind person in the country to successfully complete his medical course, is now all set to practice medicine following his registration with Delhi Medical Council.
Dr Christ Sudarshan Toppo, the first blind person to receive his MBBS degree from the All India Institute of Medical Sciences (AIIMS), has registered himself with the Delhi Medical Council and is all set to start his medical practice.

The Statesman had first reported Dr Toppo’s feat soon after he received his MBBS degree at the 33rd annual convocation of the premier medical institute.

The doctor has, however, not yet decided about his field of specialisation. “I am going through the options before me. I will make my decision only after considering all the options,” he said.

Dr Toppo was diagnosed with Eales disease, an inflammation of eye veins which causes frequent bleeding in the eyes, a month before his final MBBS exam. Following the diagnosis he had to discontinue his studies to undergo treatment.

However, once it became evident that he would not regain his vision, Dr Toppo, instead of losing heart, decided to complete his studies. He took his final exams in 2002 conducted by AIIMS and completed his internship in 2003.